What is to prevent the colored genes from spreading from these fish? They will eventually get to the wild -- enough people think that they are doing their fish a favor by releasing them when the people no longer want the fish. Further, what happens when a larger fish eats these modified danios? In most cases, the genes would probably be broken down, but what is they aren't and spread to that bigger fish? Can the scientists really be 100% sure that that won't happen? Not 99.95%, but 100%. If they are honest about it, no scientist should say they are 100% certain about anything like that.