A slow occurring bending of the spine often indicates fish Tuberculosis. Since I don't know the exact posology. and method used when treating your fishes. If you are able to get a hold on antibiotic food. I wouldn't advise not to try.
I mean, honestly you seem to have tried everything. And at this point I can sure know how you feel and my patience would be running thin.. Very thin... If I was in your place.
But can you give a hint on was have been done and how it was done.
Medication
dosage
period
water changes
anything relevant to treatment.
With general cure at first, I dosed it in the water and made medicated food with it, which I've been feeding for well over 2 weeks. After a week I did a 50% water change and added carbon. And been repeating the same every 2 weeks. Many times. (This process was done a lot of times in many tanks with no success)
Then I did the same Expel-P (Levamisole), still with no luck.
Then I tried buying all the medication fish stores recommended me, with no luck.
I've tried dosing salt in all my tanks, I've tried giving very high salt concentration baths to all my fish.
Also I've tried erythromycin antibiotic, 1 pill for every 3gal, then a 50% water change the next day followed with carbon. No luck with that ether.
Only one time I was able to partially cure an angelfish, whom was kept in a 5gal tank with a VERY high salt, general cure, expel-p concentration. He's feeling great now, it's just that he still has red gills and difficulty eating.
Also I had a bristlenose pleco die, he fell sick, but was still eating, so I kept giving him medicated algae wafers with metronidazole, praziquantel and levamisole for a month, but he stopped eating and ended up passing away as well.
Right now I'm just doing 30-50% weekly water changes and quarantine sick fish with general cure and salt. If I see one with a bent spine I just euthanise them straight away.