The cichlids are not going to hurt the pleco, he is protected by his armor. However, how big are your cichlids going to get? How big of a tank are you planning to have? My pleco has grown to about 10 inches, and is still growing. Since he is a bottom deweler, he competes with my Africans for space. He is mean and chases everyone around the tank. A giraffe cat is much more peacefull, and will keep your tank clean just as well. However, they will get realy big also and still compete with your cichlids for floor space.