Parasites

Here, the perfect treatment....., drunk fish overcome anxiety and fear  
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Friendly article: http://www.gizmag.com/drunk-zebrafish-robotic-leaf-fish/28554/
Scienfic version for TTA: http://www.plosone.org/article/info:doi/10.1371/journal.pone.0069661
 
I can't remember where I read a scientific one about fish being infected on purpose with a disease in two controlled enviroments. In one they stressed the fish first by leaving them in very little water and the other they left intact. The fish in the stressed enviroment had way higher mortality rates compared to the unstressed ones at the end of the experiment.
 
Snazy let me thank someone who states they have little or no experience dealing with recent wild imports, and certainly not with some of the most difficult ones for telling me how to do it. I expected nothing less from you.
 
Columnaris and certain types of "wasting disease" are envormental/related to bad water quality.
 
Let me quote the same Ph.D. you did regarding flubendazole
 
Eradicating Hydra and Other Pests with Flubendazole
From: Journal of the American Killifish Association September/October 2003
Vol.36, No. 5
By Charles Harrison, Ph.D.

This article is first about hydra and its eradication. Secondly, it is about a lot of relief from some of the most hideous afflictions of tropical aquarium fish, including wasting disease, which is
often associated with the presence of Hexamita, a protozoan parasite, and velvet disease, a common scourge of captive killifish which is associated with the presence of Oodinium or
Oodinium-like organisms.......
 
The hydra-killing Flubendazole that I used in my office aquarium to eradicate hydra led me to a larger realization. The “wasting” fish in that tank seemed to become cured when I added Flubendazole to the water. Whoa! This was quite a remarkable revelation. My intent was to remove the hydra and any possible nematodes and, to my surprise, the disease I have found to be
associated with a particular protozoan species was cured.
From http://www.inkmkr.com/Fish/FlubendazoleArticle.pdf
 
Read the full article- wasting disease is caused by parasites in many cases.
 
Or this
[SIZE=12pt]Myxozoa are parasites that are widely dispersed in native and pond-reared fish populations. Most infections in fish create minimal problems, but heavy infestations can become serious, especially in young fish. Myxozoans are parasites affecting a wide range of tissues........  [/SIZE]
 
[SIZE=12pt]Chronic wasting disease is common among intestinal myxozoans such as with Chloromyxum.[/SIZE]
From http://edis.ifas.ufl.edu/fa041

When wasting disease is not parasitic, it is bacterial and very hard to treat. It is caused by mycobacteria. You can do the research on that yourself if interested. But whether the wasting is caused by protazoa or by bacteria, it takes medication to cure it, not merely clean water and good acclimation practices.
 
Now on to columnaris-
Columnaris, first described by Herbert Spencer Davis in 1922, is one of the oldest known diseases of warm water fish. References to the disease can be confusing. The causative bacterium has been referred to by different names including Bacillus columnaris, Flexibacter columnaris, Cytophaga columnaris, and most recently Flavobacterium columnare.
from https://srac.tamu.edu/index.cfm/event/getFactSheet/whichfactsheet/128/
 
 


Abstract
A clinical field trial was conducted to evaluate the efficacy of aqueous chloramine-T to control mortality of goldfish (Carassius auratus) fingerlings infected with Flavobacterium columnare. In addition, the acute toxicity of chloramine-T to goldfish was determined in glass aquaria under static conditions. Chloramine-T concentrations in the toxicity test ranged from 5.0 to 40 mg/l. The concentration of chloramine-T that killed 50% of the goldfish within 24 h (24-h LC50) was estimated as 24.3±0.6 mg/l (95% confidence limits). Two days after exposing goldfish to F. columnare, fish were treated with chloramine-T ranging from 0 to 25 mg/l. None of the uninfected control fish died, and all deaths occurred between 3 and 11 days after exposure to F. columnare. Mortality of the untreated control (0 mg/l chloramine-T) group was 70% while survival of fish was significantly increased with increasing chloramine-T concentration up to 15 mg/l chloramine-T. When the concentration of chloramine-T was increased from 15 to 20 or 25 mg/l, survival of fish decreased. F. columnare was isolated from skin and gills of all fish that died during the experiments but was not isolated from survivors 21 days after exposure to bacteria. Results indicate that 15 mg/l chloramine-T can be used to treat columnaris disease in C. auratus under the experimental conditions of this study.
from http://www.sciencedirect.com/science/article/pii/S0044848604002984
 
Note- 70% of the fish infected with columnaris and left untreated died. Columnaris is a bacteria, plain and simple.
 
By "enviromental" diseases I mean those that are present in tank water and fish succumb to it when the water conditions are bad, or triggered by different/combination of stressors, etc.
Such disease examples are columnaris, hexamita or wasting disease, and many bacterial and fungal diseases.
 
When wasting disease is not parasitic, it is bacterial and very hard to treat. It is caused by mycobacteria.
Read the full article- wasting disease is caused by parasites in many cases.
 
 
OK.....
Based on your microscopic vision do you think my platy was sick from? Here are a few pictures below. He's bred by myself so not an import of any sorts.
 
First picture taken on the 20th February this year:
dscf3757lg.jpg

 
 
He started "wasting" the beginning of this year, despite having a good appetite, when one of the male platies bullied him to death and I didn't react on time. He had a caved stomach and at some stage was unable to swim properly/keep his balance. I thought he was a gonner. No other fish were introduced or any external factor that could have infected him from outside, all caused by enviromental stress of some sort.
 
He was treated with kanamycin sulphate(antibacterial antibiotic) and then a course of interpret antifungal and finrot.  He's still happily alive 6 months after. His body didn't fully recover as it was before getting sick but he's as healthy as any other one. No other fish got infected with that "wasting disease"
 
All this is anecdotal evidence because I never confirmed via a microscope what he had but he was never exposed to parasitic meds.  And if it was bacterial, then he was cured from it and it certainly wasn't mycobacteria because I'd have 5 tanks with dead fish by now.
 
4th of June this year after recovery and moved back to his own tank.
dscf4878e.jpg
 
You say the fish died because he was bullied to death. Then you say months later he is alive. I am a bit confused. Were you able to reanimate a dead fish?
 
You are aware that sometimes a sunken belly can actually be due to lack of food? Fish in stores and importers can be poorly fed. Fish in tanks can find it hard to get food when other fish bully them and prevent them from eating as well. This is a stocking issue and not a disease issue. Not all underweight fish or sunken bellies are from illness, some actually are cases of starvation.
 
You are correct about mycobacteria being hard to cure, you are not correct about the five dead tanks of fish. There are  variety of mycobacteria and not all are fatal though most resist treatment. This is why some fish with wasting disease do not respond to any treatment and simply die.
 
As for your fish, you have not provided nearly enough information to be of diagnostic use. While pretty, your pictures do nothing to show what is inside the fish. If you had at least provide one showing the fish pooping that would have helped.
 
My final comment regarding your clean water idea for disease control or curing is to remind you that pathogens are typically present in most tanks all the time. They are there is very low numbers. Healthy fish with normal immune systems can handle this. However, stressed or weak fish have their defenses compromised and this creates the opportunity for the nasties to strike. This means one need not add anything new to a tank for a fish to become sick.
 
For folks who may be interested, here is a nice paper from the University of Florida on "Stress - Its Role in Fish Disease". http://edis.ifas.ufl.edu/fa005
 
You say the fish died because he was bullied to death
 
 
TTA. the fish is alive. I'll get a video of him with todays date if you like. I said "bullied to death" as an expression. I didn't react on time as in take him out the tank on time, or the bully for that matter. Sorry for the confusion. My bad.
He wasn't starving, he was eating every day, and still is.
 
You are correct about mycobacteria being hard to cure, you are not correct about the five dead tanks of fish. There are  variety of mycobacteria and not all are fatal though most resist treatment. This is why some fish with wasting disease do not respond to any treatment and simply die.
 
 
I never knew some of them are not fatal.  But I know that once you have it in the tank, you don't get away with one sick fish if they were in contact with the other fish. To what treatment do the "non-fatal" mycobacteria infected fish respond because that's a new discovery?
 
My final comment regarding your clean water idea for disease control or curing is to remind you that pathogens are typically present in most tanks all the time. They are there is very low numbers. Healthy fish with normal immune systems can handle this. However, stressed or weak fish have their defenses compromised and this creates the opportunity for the nasties to strike. This means one need not add anything new to a tank for a fish to become sick.
 
 
That's what I was explaining all along and mentioning "envoromental" diseases. How is deworming them prior to putting in a stress enviroment going to help with that?
 
As for your fish, you have not provided nearly enough information to be of diagnostic use.
 
 
I provided more proof than you did about your fish needing to be dewormed upon introducing to your tanks.
 
For folks who may be interested, here is a nice paper from the University of Florida on "Stress - Its Role in Fish Disease". http://edis.ifas.ufl.edu/fa005
 
 
That's a great article. It's more important reading it than deworming your fish for no reason.
 
First off,  you are attributing statements to me which I never made. I defy you you to find anyplace, not only on this site, but also on any of the many other sites where I actively post now or have in the last decade, where I have ever said one should deworm and/or treat for parasites all new fish on  arrival. In fact, I defy you to find a statement by me stating all new fish should get any form of medication before one knows there is a problem or what it is.
 
However, what I have said, will continue to say and which I will debate with you indefinitely on are how to deal with most newly imported wild caught fish. Often much of this work should be done by the importer. However, given all the vagaries involved, folks who get such fish in will quarantine and do prophylactic treatments for parasites and worms. This is done for very simple reasons. Experience has taught folks that most times it is necessary. And the other side of that coin is even if there was no need to do so because the fish were totally free of these things, the medications used are so benign that there is almost 0 risk of problems. If you can find literature showing that tings like Metronidazole, Praziquantel, Flubendazole or Levamisole HCL when dosed properly cause harm to fish or have side effects that do. If you can show literature showing these things affect the nitrifying bacteria in tanks, I would be very interested in reading it.
 
While it is correct that the vast majority of mycobacterial infections can not be treated successfully, some luck has been had in this regard. Vaccines are also being developed. Some appear to be effective while others are not so. There is also a relation between the bacterial counts involved. When these are lower fish immune systems appear able to handle things. Once bacterial counts rise it is pretty much a losing battle. While some treatments have proved effective, for the most part any form of piscine mycobacteriosis is best handled by euthanizing the affected fish. However, the spreading of the disease seems to be proportional to stocking levels. the higher they are the worse things get. This illness to take anywhere from a few months to years to become fully evident, so it is entirely possible for tanks to go a very long time without everything dying.
 
Because there is no single treatment that has ever proved effective against the different strains of mycobacteria, it becomes more prudent to euthanize than to try to effect a cure.
 
Treatment
Currently there are no widely accepted treatments for mycobacteriosis in fishes. Treatment of humans infected with M. tuberculosis and opportunistic mycobacteria is typically protracted, requiring up to 24 months with multiple antibiotics. Antibiotic susceptibility testing on fish isolates is rarely performed, and resistance appears to be highly dependent on the infecting species and strain. Rifampicin, streptomycin, and erythromycin have been shown to have
some effectiveness against an undescribed Mycobacterium spp. in yellowtail (Seriola quinqueradiata) (Kawakami and Kusuda, 1990), and ethambutol, isoniazid, and/or rifampicin are  occasionally used for treating high-value specimens in aquaria (Chinabut, 1999)
. Antibiotic resistance may be a significant hurdle to treatment, however, as evidenced by isolates of M. fortuitum that were cultured from aquaria in South Africa. These isolates were found to be
resistant to standard anti-mycobacterial antibiotics including streptomycin, isoniazid, rifampicin, and ethambutol (Bragg et al., 1990). With few exceptions, the pharmacokinetics of anti-mycobacterial compounds in fishes remain unknown (e.g., Brown et al., 1990).
Unfortunately, control of mycobacteria in aquaria typically requires destruction of affected stock and disinfection of holding tanks and plumbing (Noga, 2000; Roberts, 2001).
from http://www.bfm21.com/download/latin/2.pdf
The above in red indicates treatments used going back to 1990. these are not new???
 
but then there is this:
 
 
These findings indicate that species of Mycobacterium previously undescribed from fish (i.e., M. haemophilum and M. peregrinum) may pose significant health problems in zebrafish research facilities, whereas species and strains that are already recognized as common in fish usually cause limited disease on a population basis in zebrafish.
from http://www.sciencedirect.com/science/article/pii/S1532045604001413
 
So maybe not all species of mycobateria are the same nor do they affect all fish the same.
 
But none of this has anything to do with the original topic of this thread, how to deal with the potential for parasites and worms to come in with new fish and the wisdom of automatically treating for these things on arrival (mycobacteria was only mentioned in reference to being another potential cause of wasting disease). Inin this respect I again say prophylactic treatment is situation dependent. The odds of needing to do this with tank raised fish or those farmed is fairly low as breeders and farmers normally do things to protect themselves from catastrophic losses. However, when one knows that  recently wild caught fish are mixed in the same facilities or if they are being purchased soon after they arrive in country, then yes, such prophylactic treatment is standard practice and should always be so. This is not just my opinion, talk to folks who run such breeding facilities or do the importing.
 

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