My friend runs 100 gallons worth of filtration on his 55 gallon tank. As long as the amount of food for the bacteria stays the same, there should be no difference in the amount of nitrifying bacteria in a tank with one filter and the same tank with two filters. There will be the same amount of bacteria, they'll just be spread out over a larger area. Which if you ask me is good, because if one filter dies, you still have the other one running until you can get a replacement.
The only potential problem I can see is if you have too much current for the fish you are keeping. Obviously two 20-gallon filters running in a 5 gallon tank with a betta in it would qualify as overfiltration and would not be ideal for the betta.