No, except for a few of the more delicate species, our freshwater fish can handle nitrates of 50 and often much higher. The ultimate goal is, of course, 0, but except in heavily planted tanks it's pretty much impossible to achieve without spending lots of money on medias to remove it. Most people have nitrates of 20-40 without any problems at all. Some unlucky ones even have nitrates of 40 right out of the tap.