I don't think its as hard as you make it out to be. The nanos only need a 1 or so gal WC a week. I have kept saltwater fish in my 55 gal before. I had a porcupine puffer, 3 damsels, yellow cubicus, and lion fish. They all did great, and i used crappy whisper filters with sponges in them. The hardest part was mixing the salt in the water and getting it perfect. You really must use RO/DI water for a reef though. You gonna do fish only or a reef?