Looking for fish Hexamita meds ? (alternative to api general cure)

[anewbie]

You can't treat fish TB and it's unlikely to be that if you had a fish that bloated up and then recovered. When Fish TB causes fish to bloat up, they basically swell up overnight and die within 24-48 hours of doing that. They also do a stringy white poop, stop eating and sit near the surface or filter outlet gasping for oxygen.

Fish can carry TB for years before they die. The Mycobacterium are very slow growing and can take several years before it affects an internal organ enough to cause organ failure. That's when the fish swell up and die, after an organ bursts/ ruptures from the bacteria growing in it.

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Re the tubing that has gone black inside. You can pour straight liquid bleach into the tube and leave it for an hour, then rinse it out really well. After that pour some dechlorinator down the tube and add some water and let it soak for a bit, then rinse well again.

So this begs the question of how i should treat the fish. I listed the things that haven't worked and the question is should i try epson salt or some other medicine. The fish does not sit at the top of the pail. It sits near the bottom behind the sponge filter but does come out at times and poke around. While extremely bloated (my guess is 3 to 4 times normal thickness) it actually is still swimming well and has a strong sense of balance. I been putting 2 or 3 grains of nls 1mm pellet (which has garlic). No clue if he has eaten any of it but there is a mystery snail in the pail to scavenge what he does not eat. As I said it has been in this pail for nearly 4 weeks as i try different treatment.

 

[Lajos_Detari]

So this begs the question of how i should treat the fish. I listed the things that haven't worked and the question is should i try epson salt or some other medicine. The fish does not sit at the top of the pail. It sits near the bottom behind the sponge filter but does come out at times and poke around. While extremely bloated (my guess is 3 to 4 times normal thickness) it actually is still swimming well and has a strong sense of balance. I been putting 2 or 3 grains of nls 1mm pellet (which has garlic). No clue if he has eaten any of it but there is a mystery snail in the pail to scavenge what he does not eat. As I said it has been in this pail for nearly 4 weeks as i try different treatment.

I'm not an expert in this.
I'm wondering whether you can get some antibiotic for internal treatment.

I used this before but I am not sure of its effectiveness. This product is from the UK.

Interpet - Anti Internal Bacteria Plus - 100ml

Anti Internal Bacteria Plus – 100ml | Treat systemic bacteria infections. Includes market leading breakthrough formulas for the best results.

www.interpet.co.uk

Or this brand:

Aquarium Medicine - Anti-Internal Bacteria from NT Labs

Belonging to the best range of 'Water Treatments' awarded by the Pratical Fishkeeping Manufacturers Poll. Anti-Internal Bacteria penetrates deep into the fish to locate the disease causing bacteria and eradicate them.

www.ntlabs.co.uk

You can read here for more information about the different antibiotic.
When treating bacteria infection, its important to know which type of bacteria that is causing the problem. Else, you may have to use a general type of antibiotic.

Aquarium Medications Part 2 | Antibiotic & Antimicrobial Treatments

Aquarium & Pond medications Part 2, antibiotics and antimicrobials such as Kanamycin, Triple Sulfa, Tetracycline, Metronidazole, Nitrofurazone, Neomycin, & more. Based on research from aquarium keeping guru Carl Strohmeyer

www.americanaquariumproducts.com

If not, wait for Colin to reply.

 

[anewbie]

I ordered some Fritz Maracyn Two - but I think i'll wait for @Colin to chime in because I suspect i am running out of time - there is some side damage developing from the bloat but the fish is still behaving strongly. Some reading suggest I should try a salt bath at 1 teaspoon per gallon for a few days to reduce the swelling and then try a bacteria treatment. I have 1 or 2 packets of furan-2 left but you can't buy it anymore (fda in america decided to ban selling of most fish medicine 2 or 3 months ago and most of the drugs have been pulled).

 

[Lajos_Detari]

By the way, have you tried Metronidazole?

According to the website below, Metronidazole combine with Neomycin can treat fish bloating of digestive tract.
Probably a combination of both is more effective.

Aquarium Medications Part 2 | Antibiotic & Antimicrobial Treatments

Aquarium & Pond medications Part 2, antibiotics and antimicrobials such as Kanamycin, Triple Sulfa, Tetracycline, Metronidazole, Nitrofurazone, Neomycin, & more. Based on research from aquarium keeping guru Carl Strohmeyer

www.americanaquariumproducts.com

METRONIDAZOLE:​

USE: Metronidazoles primary use is for the treatment of anaerobic gram positive bacteria including those that produce beta-lactamase. However, it is not effective against aerobic bacterium.
As well Metronidazole is effective for some protozoa (especially internal flagellates).

Due to Metronidazole effectiveness against anaerobic bacteria (by selectively blocking some of the cell functions of anaerobic bacteria) this drug along with Neomycin is a good choice for bloating of the digestive tract (common in goldfish). Metronidazole when combined with Neomycin sulfate in a medicated fish food slurry can be a very good full spectrum internal/gut infection treatment, treating both aerobic and anaerobic bacterium.
Metronidazole selectively blocks some of the cell functions in anaerobic bacteria, resulting in their demise.

NEOMYCIN SULFATE:​

USE: Neomycin (a Aminoglycoside) is a broad spectrum antibiotic that is effective for aerobic gram-positive, some gram-negative such as Aeromonas of the gut, and occasionally Mycobacterium tuberculosis (Mycobacterium marinum), which is neither Gram-positive nor Gram-negative due to high lipid content in its wall.
Neomycin is poorly absorbed internally. The lack of absorption from the gastrointestinal tract is the basis of the main use of Neomycin.

Effective for some Gram-negative bacteria- Open red sores or ulcerations, intestinal infections, fin and tail damage. As noted, Neomycin can be effective for wounds, ulcerations, or large sores, however I have found best results when used in combination with Triple Sulfa for such issues (used in a fish bath at double dose can also yield better results).

In severe cases where fins and tail are eaten away- treat with Kanamycin for this.
As well, Neomycin can be PART of a treatment for mycobacterium tuberculosis (symptoms, weight loss, a distended abdomen, loss of appetite, fin erosion, unusual coloration, spinal deformities, and listless behavior).

Aminoglycosides such as Neomycin are mostly ineffective against anaerobic bacteria, fungi, yeast, and viruses.

Neomycin is not absorbed by the intestinal tract and is effective in treatment of diseases thereof. But Neomycin can damage the kidneys as it is nephrotoxic when it enters the bloodstream, however since this drug is not readily absorbed in the intestinal tract it is useful for treatment of pathogens such as Aeromonas, particularly of the gut, that can lead to Dropsy or similar disease.

 

[anewbie]

By the way, have you tried Metronidazole?

According to the website below, Metronidazole combine with Neomycin can treat fish bloating of digestive tract.
Probably a combination of both is more effective.

Aquarium Medications Part 2 | Antibiotic & Antimicrobial Treatments

Aquarium & Pond medications Part 2, antibiotics and antimicrobials such as Kanamycin, Triple Sulfa, Tetracycline, Metronidazole, Nitrofurazone, Neomycin, & more. Based on research from aquarium keeping guru Carl Strohmeyer

www.americanaquariumproducts.com

METRONIDAZOLE:​

USE: Metronidazoles primary use is for the treatment of anaerobic gram positive bacteria including those that produce beta-lactamase. However, it is not effective against aerobic bacterium.
As well Metronidazole is effective for some protozoa (especially internal flagellates).

Due to Metronidazole effectiveness against anaerobic bacteria (by selectively blocking some of the cell functions of anaerobic bacteria) this drug along with Neomycin is a good choice for bloating of the digestive tract (common in goldfish). Metronidazole when combined with Neomycin sulfate in a medicated fish food slurry can be a very good full spectrum internal/gut infection treatment, treating both aerobic and anaerobic bacterium.
Metronidazole selectively blocks some of the cell functions in anaerobic bacteria, resulting in their demise.

NEOMYCIN SULFATE:​

USE: Neomycin (a Aminoglycoside) is a broad spectrum antibiotic that is effective for aerobic gram-positive, some gram-negative such as Aeromonas of the gut, and occasionally Mycobacterium tuberculosis (Mycobacterium marinum), which is neither Gram-positive nor Gram-negative due to high lipid content in its wall.
Neomycin is poorly absorbed internally. The lack of absorption from the gastrointestinal tract is the basis of the main use of Neomycin.

Effective for some Gram-negative bacteria- Open red sores or ulcerations, intestinal infections, fin and tail damage. As noted, Neomycin can be effective for wounds, ulcerations, or large sores, however I have found best results when used in combination with Triple Sulfa for such issues (used in a fish bath at double dose can also yield better results).

In severe cases where fins and tail are eaten away- treat with Kanamycin for this.
As well, Neomycin can be PART of a treatment for mycobacterium tuberculosis (symptoms, weight loss, a distended abdomen, loss of appetite, fin erosion, unusual coloration, spinal deformities, and listless behavior).

Aminoglycosides such as Neomycin are mostly ineffective against anaerobic bacteria, fungi, yeast, and viruses.

Neomycin is not absorbed by the intestinal tract and is effective in treatment of diseases thereof. But Neomycin can damage the kidneys as it is nephrotoxic when it enters the bloodstream, however since this drug is not readily absorbed in the intestinal tract it is useful for treatment of pathogens such as Aeromonas, particularly of the gut, that can lead to Dropsy or similar disease.

What would the dosage be if i used both together - the dosage as if each was used sep or 1/2 of one and 1/2 of the other ?

Other than the extreme bloat and pale look the fish actually looks normal - no damage to fins - there is some damage starting in mid body due to (i believe) extreme bloat).

 

[Lajos_Detari]

What would the dosage be if i used both together - the dosage as if each was used sep or 1/2 of one and 1/2 of the other ?

Other than the extreme bloat and pale look the fish actually looks normal - no damage to fins - there is some damage starting in mid body due to (i believe) extreme bloat).

Sorry, I have not used these medications before.
For precaution, perhaps you can use one type first and follow the manufacturer dosage. Use a second type on the following if they don't recover.
Or probably search the internets for more information to find out how to use both together.

Here are some studies on using both medications.

Importance of adding neomycin to metronidazole for bowel preparation

A prospective randomized trial has investigated whether it is necessary to add oral neomycin to oral metronidazole as a means of preventing sepsis in elective colonic resection. Seventy-three patients completed the study; 41 received metronidazole and ...

www.ncbi.nlm.nih.gov