The flashing seems to have calmed down after a 75% water change. So I am hoping it just the ammonia in the water if there was any present rather than some sort of infection. However I will be keeping a close eye on them for any further symptoms. Does salt fight against most infections/diseases? I forgot to add in the previous post there is nothing else in the tank apart from the 3 guppies. I am hoping to carry out a gravel clean today and another 75% water change. Many thanks for your help.