Littleimp, note:
I think I'm going to start with a FOWLR setup then slowly go up to a reef tank.
Ahem!!
If you want to run this as a fish only set-up you could use 2 large canister filters (fx-5's or similer) to run this tank. Marine keepers have been doing this for yonks. It's only in recent years that the berlin method of live rock & flow has become the norm & popular. The berlin method has allowed more & more people to keep a reef tank, that's the difference. High nitrates are toxic to corals but many fish can be kept like this as some of the older 'reefers' will testify.
Littleimp, fish-r-fancy plans to set-up a reef, after going FOWLR. Trust me, when you start FOWLR, and get to know how the hype of SW being so much more difficult than FW is a load of rubbish, you soon want to start adding corals when you improve lighting.
Why start with 2 large expensive cannisters when all you need is LR and powerheads to accomplish filtration? LR and your powerheads can be used later in a reef situation. Cannisters should be stripped off once you start a reef. You could use a smaller eheim cannister to run rowaphose and carbon, but two FX-5's are way too big, so it would be an initial waste of money, for something that you going to remove later. They'd also consume masses of cupboard space, so youd miss out on a certainextra volume added by the way of a sump or refugium.
Your fish/LR need flow, even if you went FOWLR. With two FX-5's your looking at 4.18x turnover for total tank volume, where as compare two Tunze 6100 Turbelles and your looking at 21.8 times turnover, which is alot better.
It doesnt take an old 'reefer' to tell you fish survive nitrate, fish do, its just not the best possible condition you can have your tank in. The term 'reefer' implies they kept a reef in high nitrate, but many of the older folks couldnt keep coral alive, and they didnt keep reefs, they kept fish.
The berlin method is now the norm and popular because it offers many more advantages, and is genuinly considered superior to cannisters/mechanical filtration.
If it were me, Id go LR with powerheads, that way I wouldnt have to buy cannisters and stop using them when I went reef. All id have to buy is better lights and im away. If you want FOWLR, you dont need a cannister either (because of the LR), but fish can survive certain levels of nitrate.