For a long time, I couldn't get water soluble nematode treatments. I had to use dog dewormers, til they came under veterinary prescription too. The local vets say they have not studied fish, so they would consider it unprofessional to prescribe for them. That's a quandary, but I'm a little over an hour north of Maine and there, I can gets meds. There's a Tractor Supply place that makes me think American tractors must have 40 foot tapeworms.
I won't buy antibiotics out of principle, but dewormers? Yeah.
I can also get water soluble nematode treatments now.
But what I did was take a little white flashed fish and hit it with the stick blender. I'd add some baby food veggies and some meds, and freeze it. Then I'd thaw tiny chunks and do a 3 week course, which did the job very well. No fish died, and no Camallanus or Capillaria seemed to survive.
I'm certain that every fish that comes from the wild has worms. But I think there's a balance internally, just as there is with us if we're healthy and get run of the mill tapeworms and such. For farmed fish, I think the crowding means they are exposed to parasite loads their immune systems can't control. And so we get sick fish, in many cases. I've noticed that when I get wild caught Asian fish, I often need to treat them. I think it's because they are delivered to the farms/exporters to go on the lists, and they pick up a parasite load in the holding tanks. It's easily dealt with.
South American and African exporters don't usually have breeding farms, but exclusively wild stock.
Anecdotes - not science. But it is very easy and quick (if messy) to make medicated foods.
I've been mentally torn about the issue of medicating in quarantine too, especially when getting fish from a "rescue" tank, that likely came from a store/farmed abroad, or fish I've bought myself from a store.
I usually QT for a month, but especially with livebearers, I've been worming using the eSHa meds since I've personally found them to be effective, and not wanting to re-introduce worms into my main tanks after working so hard to eradicate them, and of course the cost of medicating the larger tanks. But I wonder about recommending that to other hobbyists, and it doesn't really fit in with my usual hope of using the minimal amount of chemicals and products in my hobby.