I'm not a pleco guy, so I've never bred them and have rarely even owned them. That being said, I've bred many fish over the years I've been in the hobby so I've got a couple of things to say that may be worth considering before you attempt to breed.
With fish of any kind you would need to consider what you would do with the offspring if you were successful in breeding them.
Is there a market for the more common bristlenose (or whichever pleco you pick) where you live? I know there isn't near me, they are being given away for free by amateur breeders and sold for next to nothing in my local fish shops.
I was offered a tank full a couple of months ago, but I was unwilling to take on another guys problem. There were over 100 for sure, and supposedly they had only bred once.
I'd caution you against choosing something that is so prolific a breeder. Google is telling me that they can lay up to about 200 eggs per month once they reach breeding age, and if that is accurate you could quickly become quite overwhelmed.
As I say, they are given away for free where I live, so I'm not sure how much money you would be able to make on them.
All that being said, if you choose to try breeding them I wish you well.
