I'm going both ways on this. If you don't want a DSB then why get rid of it? If you do, I think you can get away with adding the extra 4" of sand but well, why take the risk. As for getting it out, I'd take everything out of the tank and then remove the substrate then add the new the put the stuff back (assuming live rock is in there?).
How long has the tank been running?
Oh, and "live sand" is not live sand, in fact. The stuff in bags has bacteria only. Basically it is doing nothing for you. You need to seed the sandbed with pods and worms. Do a search and you'll find bunches. Check out aquabid.com under marine inverts or floridapets.com (I think) if you are in the US. Or, best yet, check out Robert Sullivan's auctions on ebay (search on the word "detritivore") -- what you really need is a detritivore kit like he sells.
You can and should also get cups of sand and mud from established systems and from reliable suppliers of cured live rock. Ask them for a bag of mud and they will know what you are talking about. If they don't know, then don't buy anything for a reef from them as their stock will not be reliably healthy.