Not really, it just means you have to wait until everything dies, breaksdown, and your reading of nitrates, nitrites, and ammonia are zero. If you buy fully cured LR, you wont have the die off, and youll have less time to wait, as you almost have a completly cycled tank.
Cured LR will cost more though, so if you have patience, and want to save some dough, you could buy un-cured LR.