Imo i would never use nothing no matter if it says reef safe or not in my display tanks, that is what there is Qt tanks for to do hyposalinty, treat them if needed, to leave them in there for 4-6 weeks to make sure there as healthy as they can be and well fed so there immune system is well built up before the fish gets put into the display tank where this fish may also get picked on which can cause problems. Also a lot of stuff that says it is reef safe isnt total reef safe. Most kill good stuff that live in your live sand.