Fish allergens... not going where you might think...

Magnum Man

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@GaryE 's response to my fish food packaging thread made me think of this... I wonder if fish could have allergies like humans??? Gary's response was, ... peanut butter jars, and noting that a lot of prepared fish foods contain wheat, if some of the fish deaths out there could be related to allergies... hey, even shellfish???
 
Interesting line of thought. Even if we feed insects to insectivores, we probably don't feed the same species they are adapted to eating in nature. So whatever they eat they could be allergic to - their bodies are complex enough for that. The ladybug talk in another thread leads there - bugs can have toxic defenses, but there are a few predators that can eat ladybugs. Evolution's the greatest story ever.

My attempt to see if I could get deeper info n this just got me hits for us being allergic to fish.

It seems to me to be more stuff to learn we don't know much about.
 
there are always those unexplained deaths, of one fish, when the rest are fine....

maybe a group of really had to keep fish, are actually allergic to wheat, and since that is in nearly every prepared food... the fish might turn out to be easy to keep, as long as they didn't get fed, a food which wheat in it???
 

Towards an optimized model of food allergy in zebrafish​

Jiali Bao 1, Yushu Qiu 2, Xinyi Xu 3, Xiao Fu 4, Jingjing Song 3, Lei Wang 3, Lisu Huang 5, Weixi Zhang 6

Abstract​

Background: The prevalence of food allergies is on the rise, posing a significant challenge to public health. Rodents serve as the predominant animal model in food allergy research; yet, the application of rodent models proves to be a laborious and time-consuming endeavor. It is imperative to develop novel in vivo models.
Methods: Ovalbumin (OVA) was administered as the allergen, following the recommended dosage used in other species. During the sensitization phase, a dosage of 0.25 mg per 10 tails per 1 L was administered twice daily, and during the challenge phase, the dosage was increased to 3 times the initial level. The study explored two dimensions of sensitization: the mode of exposure, which can be either continuous or intermittent, and the duration of exposure, which includes 3 days, 5 days, and 7 days. We examined midgut pathological changes, immunoglobulins contents, and mRNA expressions associated to T helper cells (Th) 2 cytokines following exposure.
Results: A significant 109.3 % increase in the number of eosinophils was observed in the midgut histopathology following intermittent 5-day OVA exposure, which emerged as the most effective model. OVA exposure increased concentrations of immunoglobulin M (IgM) (105.2 %), IgZ (312.1 %), and IgD (304.3 %) in this model. The mRNA expressions of Th2-related interleukin (IL)-4 and IL-13 were also elevated by 132.8 % and 421.0 %, respectively.
Conclusion: The intermittent 5-day OVA exposure was suggested to be the best constructed zebrafish food allergy model, which may be a potential tool for research into food allergies.
 
Why wheat though? That sounds a bit like a human problem being expected in fish. They have allergens but wheat would be so far out there in their diet. It's been a cheap bulk filler in prepared foods for decades. But a number of hobbyists use almost no prepped foods.
 
Who is not using any prepped food ? Besides a couple of exceptions who go out of their way...

The standard far from MTS home hobbyists with a platy tank for the kids... I know one like that... And besides never changing an ounce of water once in 15 years, is still feeding them flakes he bought in bulk at he same time. And there's not a single plant in there.

But for a reason I sure don't want to know... They are thriving. I'm not even thinking about nitrate level.
 
honestly the bulk of my food ( for lack of time ) is still prepared foods, I feed on the average, 3 different kinds, at the same time, once a day... I probably have a dozen kinds to choose from, in the rotation... it's virtually impossible to find a food, that only contains ingredients the fish could access in the wild... I do feed good quality frozen foods, at least once per week, and when I actually get to where I can retire ( I can see the light at the end of the tunnel, at least ), I'd like to do a few live foods... but that leaves a lot of food ingredients out there that could be killing fish, or at least irritating their digestive system
 
honestly the bulk of my food ( for lack of time ) is still prepared foods, I feed on the average, 3 different kinds, at the same time, once a day... I probably have a dozen kinds to choose from, in the rotation... it's virtually impossible to find a food, that only contains ingredients the fish could access in the wild... I do feed good quality frozen foods, at least once per week, and when I actually get to where I can retire ( I can see the light at the end of the tunnel, at least ), I'd like to do a few live foods... but that leaves a lot of food ingredients out there that could be killing fish, or at least irritating their digestive system

I thought Prepped food is the one you get and drop in.... When you say prepped you mean you prepared it ???

Want to be sure. Because prepped food for me, is the one you put directly cold in mouth.

And it doesn't need a still to distillate paramecia to feed flagellates for a flourishing biofilm ;)
 
Ian Fuller, the guy who is top knowledgeable on all things corydoras, has mentioned that there are species of corydoras who have higher odds of being allergic to bloodworms.


Interestingly, when I had my hoplisoma weitzmani, any time I fed bloodworms, they'd develop excess slime and constantly flash. Not knowing at the time the cause, I figured external parasites, treat for them, but it would keep happening. As I learned about some cories reacting this way to bloodworm, I stopped feeding them bloodworms altogether. Excess slime coat and the flashing went away.

I noticed my osteogaster eques react the same with bloodworm, so they don't get it either and I've stopped feeding it at all to any of my cories. Only my betta gets them regularly, and my frogs get them as a once a month treat. I've switched to brine or mysis shrimp instead for frozen foods.
 

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