Erm, no, start with an empty canister or you get air locks IME
Empty everything. Position the filter benieth the tank and position the inlet and outlet where you want them in the tank. Next, plumb up by running hoses from each inlet/outlet set to the filters inlet/outlet connector. Keep the hoses as short as possible to get the most possible flow when in operation

Now check that both taps are open. If it's a Pro2, press the self-prime button a few times, for a Pro1 you will have to suck the outlet at this point. (I can't remember if the 2227 is a Pro1/2, sorry

) Now go and make a cup of tea (very important that bit) while the filter fills up and "primes". Now, once full (after about 2-5 mins) plug it in and off it should go. After a few moments of funny noises if should all settle down
All the best
Rabbut