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Another possibility is internal parasites, as loss of appetite and inactivity are common symptoms of them - especially if your puffer's stomach looks skinny and pinched. Walmart's GSPs are usually in pretty bad shape...it seems like at least half the ones I see there are starved and/or...

I think Melafix would help a lot. I had this with one of my GSPs about two weeks ago, along with a small white patch on her dorsal fin. I treated with both Melafix and Pimafix immediately and continued for a week and a couple of days and then stopped the Pimafix. I'm still treating with...