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Before and after mardel maracyn for 5 full days. End of treatment with no improvement. Thanks to everyone for your advice and comments.

Thanks for the info. I guess I'm not too surprised to learn that. I recall reading a while ago that a lot of genetic markers for various cancers have been identified, but that was in humans. This makes it even more a complicated decision.

You are right. I decided that I would do my due diligence and complete the 5 day treatment, and if there was no improvement, I would put down the fish. I have one other female in addition to this one that have over the 8 months or so produced about 16 fry. Unfortunately this one still has a...

Comparison photos before and after treatment with mardel maracyn for 2 full days. There doesn't seem to be any noticeable improvement.

Hoping for the best, expecting the worst.

Yeah, that seems like a distinct possibility. Since there isn't much that can be done if it is cancerous, I'm just doing what I can hoping that it is fin rot. I will provide updates. Thanks for your comment.

Just finished isolating the guppy into a 5 gallon pail with a sponge filter. I am treating with mardel maracyn, and will do this for 5 days as recommended by Fritz Aquatics. I will post photos every few days. Fingers crossed. Thanks again.

Thanks for your comments. Starting tomorrow, I'm going to isolate this guppy, and treat it for fin rot seeing as that's the only possible remedy I can think of for now. As far as I can tell, none of the other guppies or striped danios (4 of them) in the same tank have anything like it. But...

Thank you for your comments. All the examples of fins changing to black on guppies did not appear to have the fin actually deteriorating or getting eaten away as in this case. Based on your comment, and the one that followed yours, I'm beginning to think it may be fin rot, or maybe even...

I've been keeping kohaku guppies for about a year. Of the four that I have, one of them has developed a black spot on it's tail fin. I noticed this about a week ago, and need to know how to treat it, and if it should be isolated. I've looked on the internet for info but can't find anything...

I am a returning aquarium fish keeper, first set up aquariums in my early twenties. Now retired, started again about a year ago. For now, sticking with simple, hardy fish (danios, guppies). Looking forward to learning and sharing with the group.