I would think i tworks fine to keep 8 clown loaches in a 400 gallon tank; but your statement seems to imply that clown loaches are simply too large for any size tank... or perhaps i misunderstood.
I would say that clown loaches are to be avoided by all but the people with the largest tanks. They're sold in stores as young juveniles, and grow. They live over 30 years. If you have a huge tank already and love the fish dearly, then you can make a go of it. But keeping them alive for 5 years? Nah. That's not a success.
We like the idea they grow slowly, but I guess when you've had fish for a long time as I have, slowly becomes relative. Whether you see an accident in slow motion or sped up, there's still a crunch.
I think we can present such opinions without people launching personal attacks. I may be wrong, but I'm not incoherent. I'll argue against all big fish in small tanks. I tried these things, and I have seen many do the same as I did. I was able to rehome my Satanoperca daemon, I sold my adult red-head Tapajos and winemilleri and I was responsible for the early deaths of my clown loaches. I didn't enjoy any of that. I needed tanks larger than my 6 footer.
My slowly developed rule of thumb for Cichlids, since I am into them for their behaviour, is that you research the largest adult size, then provide them with a tank with a front glass 10 times that length, and you're probably at a good start. If they're one inch long when you buy them, heading for 12, then 120 inches it is, or no buy. There are other projects galore. I think the same rule applies to fish like clown loaches.
Big fish in large tanks are a different story. I have a friend with a 16 foot tank, and an eight foot square acrylic. He has a really nice set up in the 16 footer, with some large fish kept properly. The tank is bigger than a trailer, and is kind of astonishing to sit back and watch. Every detail is designed to emulate the natural environment of the fish.
I think that in our hobby, we make a serious mistake when we think we can make fish adapt to us. We have a wonderful opportunity to learn with fish, but lesson five (no one gets there in year one) is that the lifestyle of the fish comes first, otherwise, what are you watching? It's the lion in the old fashioned zoo cage versus the lion you have to stand for a bit and watch for because the zoo has a more natural enclosure. Fewer fish, no crowding, appropriate sized tanks - we can make habitats that no one will look at and wonder how a fish survives in such conditions. Or, why a fish survives in crammed tanks.