In my experience, both having kept mollies, and having seen countless such threads on this forum, mollies seem to have a definite weakness for this.
"Popeye" caused by an illness tends to affect both eyes, and none of my mollies ever had the condition affect both. However, all of my mollies, at one time or another, suffered from the single-eye version. Daily water changes, of around 20%, for 4-5 days will probably sort the problem.